Messi was left out of Barca’s unconvincing round of 32 victory over Ibiza last week, but Setien restored the six-time Ballon d’Or winner to his starting line up in Thursday’s last-16 clash.
Goals from Antoine Greizmann and Clement Lenglet gave the Blaugrana a comfortable half-time lead at Camp Nou, as they put the disappointment of a 2-0 La Liga defeat at Valencia on Saturday firmly behind them.
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